| Award | Player | Team |
| Player of the Year | Domanick Davis | Houston |
| Front Office Bowl MVP | Peyton Manning | Cleveland |
| Coach of the Year | Jimmie Endres | New Orleans |
| Legend of the Game | Willie McGinest | New England |
| Offensive Player of the Year | Domanick Davis | Houston |
| Defensive Player of the Year | Angelo Crowell | Buffalo |
| Offensive Rookie of the Year | Reggie Bush | New England |
| Defensive Rookie of the Year | D'Qwell Jackson | Houston |
| All-League First Team Quarterback | Peyton Manning | Cleveland |
| All-League First Team Running Back | Domanick Davis | Houston |
| All-League First Team Fullback | Quentin Springer | New Orleans |
| All-League First Team Tight End | Mike Seidman | Carolina |
| All-League First Team Wide Receiver | Charles Rogers | Detroit |
| All-League First Team Wide Receiver | Rasheed Marshell | Jacksonville |
| All-League First Team Center | Adam Treu | Oakland |
| All-League First Team Offensive Guard | Claude Terrell | San Francisco |
| All-League First Team Offensive Guard | Logan Mankins | Chicago |
| All-League First Team Offensive Tackle | Tom Ashworth | New England |
| All-League First Team Offensive Tackle | Dana Casares | Minnesota |
| All-League First Team Punter | Wes Stevenson | Philadelphia |
| All-League First Team Kicker | Adam Vinatieri | Houston |
| All-League First Team Defensive End | Kenechi Udeze | Detroit |
| All-League First Team Defensive End | Jason Taylor | Houston |
| All-League First Team Defensive Tackle | Bryce Barton | New Orleans |
| All-League First Team Defensive Tackle | Dewayne Robertson | San Francisco |
| All-League First Team Inside Linebacker | Terry Pierce | Denver |
| All-League First Team Outside Linebacker | Angelo Crowell | Buffalo |
| All-League First Team Outside Linebacker | Karlos Dansby | St. Louis |
| All-League First Team Cornerback | Samari Rolle | Tennessee |
| All-League First Team Cornerback | Terence Newman | Dallas |
| All-League First Team Safety | Rashean Mathis | Jacksonville |
| All-League First Team Safety | Adam Archuleta | St. Louis |
| All-League Second Team Quarterback | Chad Pennington | Houston |
| All-League Second Team Running Back | William Green | Cleveland |
| All-League Second Team Fullback | Dan Kreider | Philadelphia |
| All-League Second Team Tight End | Allen Atkins | Baltimore |
| All-League Second Team Wide Receiver | Jamie Woods | Tampa Bay |
| All-League Second Team Wide Receiver | Anquan Boldin | Jacksonville |
| All-League Second Team Center | David Baas | Philadelphia |
| All-League Second Team Offensive Guard | Edwin Mulitalo | Miami |
| All-League Second Team Offensive Guard | Trey Darilek | Baltimore |
| All-League Second Team Offensive Tackle | Jeff Backus | St. Louis |
| All-League Second Team Offensive Tackle | Nat Dorsey | Houston |
| All-League Second Team Punter | Adam Finley | Denver |
| All-League Second Team Kicker | David Akers | San Diego |
| All-League Second Team Defensive End | Patrick Kerney | Atlanta |
| All-League Second Team Defensive End | Demarcus Ware | Jacksonville |
| All-League Second Team Defensive Tackle | Ricky Hanks | Seattle |
| All-League Second Team Defensive Tackle | La'Roi Glover | San Diego |
| All-League Second Team Inside Linebacker | Morlon Greenwood | Atlanta |
| All-League Second Team Outside Linebacker | Raonall Smith | Jacksonville |
| All-League Second Team Outside Linebacker | Rosevelt Colvin | Minnesota |
| All-League Second Team Cornerback | Mike McKenzie | Green Bay |
| All-League Second Team Cornerback | Chris McAlister | San Diego |
| All-League Second Team Safety | Aric Morris | Detroit |
| All-League Second Team Safety | Tank Williams | Tennessee |
| League's Fastest Man | Jason McAddley | New Orleans |
| League's Strongest Man | Jon Stinchcomb | Miami |